15-YEAR BORRELIA PREVALENCE AND SPECIES DISTRIBUTION MONITORING IN IXODES RICINUS/INOPINATUS POPULATIONS IN THE CITY OF HANOVER, GERMANY

15-year Borrelia prevalence and species distribution monitoring in Ixodes ricinus/inopinatus populations in the city of Hanover, Germany

Lyme borreliosis, caused by Borrelia burgdorferi sensu lato (s.l.) spirochaetes, is the most common tick-borne disease (TBD) in the Northern Hemisphere.Rising incidences indicate that its epidemiology may be affected by global changes.Therefore, the current study aimed to assess changes in tick infection rates with Borrelia spp.over a 15-year monit

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Chemotherapy-elicited exosomal miR-378a-3p and miR-378d promote breast cancer stemness and chemoresistance via the activation of EZH2/STAT3 signaling

Abstract Background Not all breast cancer (BC) patients who receive neoadjuvant chemotherapy achieve a pathologic complete response (pCR), but the reasons for this are unknown.Previous studies have shown that exosomes produced in the tumor microenvironment in response to chemotherapy promote a chemotherapy-resistant phenotype in tumors.However, the

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